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Proteolytic α-Synuclein Cleavage in Health and Disease

In Parkinson’s disease, aggregates of α-synuclein within Lewy bodies and Lewy neurites represent neuropathological hallmarks. However, the cellular and molecular mechanisms triggering oligomeric and fibrillary α-synuclein aggregation are not fully understood. Recent evidence indicates that oxidative...

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Dettagli Bibliografici
Pubblicato in:Int J Mol Sci
Autori principali: Bluhm, Alexandra, Schrempel, Sarah, von Hörsten, Stephan, Schulze, Anja, Roßner, Steffen
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8196865/
https://ncbi.nlm.nih.gov/pubmed/34064208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22115450
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