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Plasma biomarkers of Alzheimer’s disease improve prediction of cognitive decline in cognitively unimpaired elderly populations

Plasma biomarkers of amyloid, tau, and neurodegeneration (ATN) need to be characterized in cognitively unimpaired (CU) elderly individuals. We therefore tested if plasma measurements of amyloid-β (Aβ)42/40, phospho-tau217 (P-tau217), and neurofilament light (NfL) together predict clinical deteriorat...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Cullen, Nicholas C., Leuzy, Antoine, Janelidze, Shorena, Palmqvist, Sebastian, Svenningsson, Anna L., Stomrud, Erik, Dage, Jeffrey L., Mattsson-Carlgren, Niklas, Hansson, Oskar
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8196018/
https://ncbi.nlm.nih.gov/pubmed/34117234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23746-0
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