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Plasma biomarkers of Alzheimer’s disease improve prediction of cognitive decline in cognitively unimpaired elderly populations

Plasma biomarkers of amyloid, tau, and neurodegeneration (ATN) need to be characterized in cognitively unimpaired (CU) elderly individuals. We therefore tested if plasma measurements of amyloid-β (Aβ)42/40, phospho-tau217 (P-tau217), and neurofilament light (NfL) together predict clinical deteriorat...

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Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Cullen, Nicholas C., Leuzy, Antoine, Janelidze, Shorena, Palmqvist, Sebastian, Svenningsson, Anna L., Stomrud, Erik, Dage, Jeffrey L., Mattsson-Carlgren, Niklas, Hansson, Oskar
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2021
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8196018/
https://ncbi.nlm.nih.gov/pubmed/34117234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23746-0
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