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Plasma biomarkers of Alzheimer’s disease improve prediction of cognitive decline in cognitively unimpaired elderly populations

Plasma biomarkers of amyloid, tau, and neurodegeneration (ATN) need to be characterized in cognitively unimpaired (CU) elderly individuals. We therefore tested if plasma measurements of amyloid-β (Aβ)42/40, phospho-tau217 (P-tau217), and neurofilament light (NfL) together predict clinical deteriorat...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Cullen, Nicholas C., Leuzy, Antoine, Janelidze, Shorena, Palmqvist, Sebastian, Svenningsson, Anna L., Stomrud, Erik, Dage, Jeffrey L., Mattsson-Carlgren, Niklas, Hansson, Oskar
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8196018/
https://ncbi.nlm.nih.gov/pubmed/34117234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23746-0
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