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Dendritic spines are lost in clusters in Alzheimer’s disease

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by a deterioration of neuronal connectivity. The pathological accumulation of tau in neurons is one of the hallmarks of AD and has been connected to the loss of dendritic spines of pyramidal cells, which are the major...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Mijalkov, Mite, Volpe, Giovanni, Fernaud-Espinosa, Isabel, DeFelipe, Javier, Pereira, Joana B., Merino-Serrais, Paula
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8196005/
https://ncbi.nlm.nih.gov/pubmed/34117272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-91726-x
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