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Dendritic spines are lost in clusters in Alzheimer’s disease

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by a deterioration of neuronal connectivity. The pathological accumulation of tau in neurons is one of the hallmarks of AD and has been connected to the loss of dendritic spines of pyramidal cells, which are the major...

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Detalhes bibliográficos
Publicado no:Sci Rep
Principais autores: Mijalkov, Mite, Volpe, Giovanni, Fernaud-Espinosa, Isabel, DeFelipe, Javier, Pereira, Joana B., Merino-Serrais, Paula
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8196005/
https://ncbi.nlm.nih.gov/pubmed/34117272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-91726-x
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