Metastasis-suppressor NME1 controls the invasive switch of breast cancer by regulating MT1-MMP surface clearance

Membrane Type 1 Matrix Metalloprotease (MT1-MMP) contributes to the invasive progression of breast cancers by degrading extracellular matrix tissues. Nucleoside diphosphate kinase, NME1/NM23-H1, has been identified as a metastasis suppressor; however, its contribution to local invasion in breast can...

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Pubblicato in:Oncogene
Autori principali: Lodillinsky, Catalina, Fuhrmann, Laetitia, Irondelle, Marie, Pylypenko, Olena, Li, Xiao-Yan, Bonsang-Kitzis, Hélène, Reyal, Fabien, Vacher, Sophie, Calmel, Claire, De Wever, Olivier, Bièche, Ivan, Lacombe, Marie-Lise, Eiján, Ana Maria, Houdusse, Anne, Vincent-Salomon, Anne, Weiss, Stephen J., Chavrier, Philippe, Boissan, Mathieu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8195739/
https://ncbi.nlm.nih.gov/pubmed/34012098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-021-01826-1
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