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Implications of diffusion and time-varying morphogen gradients for the dynamic positioning and precision of bistable gene expression boundaries

The earliest models for how morphogen gradients guide embryonic patterning failed to account for experimental observations of temporal refinement in gene expression domains. Following theoretical and experimental work in this area, dynamic positional information has emerged as a conceptual framework...

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Pubblicato in:PLoS Comput Biol
Autore principale: Perkins, Melinda Liu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8195430/
https://ncbi.nlm.nih.gov/pubmed/34061823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008589
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