Metabolic radiolabeling and in vivo PET imaging of cytotoxic T lymphocytes to guide combination adoptive cell transfer cancer therapy

BACKGROUND: Adoptive T cell transfer-based immunotherapy yields unsatisfactory results in the treatment of solid tumors, partially owing to limited tumor infiltration and the immunosuppressive microenvironment in solid tumors. Therefore, strategies for the noninvasive tracking of adoptive T cells ar...

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Dettagli Bibliografici
Pubblicato in:J Nanobiotechnology
Autori principali: Lu, Dehua, Wang, Yanpu, Zhang, Ting, Wang, Feng, Li, Kui, Zhou, Shixin, Zhu, Hua, Yang, Zhi, Liu, Zhaofei
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2021
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8194184/
https://ncbi.nlm.nih.gov/pubmed/34112200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-021-00924-2
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