The stemness of hepatocytes is maintained by high levels of lipopolysaccharide via YAP1 activation

BACKGROUND: The liver possesses a powerful regeneration ability, which is correlated with the stemness of hepatocytes in the portal vein (PV). However, the mechanism underlying the maintenance of hepatocyte stemness has not been elucidated. Here, we hypothesized that high levels of lipopolysaccharid...

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Vydáno v:Stem Cell Res Ther
Hlavní autoři: Shao, Changchun, Yang, Xue, Jing, Yingying, Hou, Xiaojuan, Huang, Yihua, Zong, Chen, Gao, Lu, Liu, Wenting, Jiang, Jinghua, Ye, Fei, Shi, Junxia, Zhao, Qiudong, Li, Rong, Zhang, Xiaoren, Wei, Lixin
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2021
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8193885/
https://ncbi.nlm.nih.gov/pubmed/34112239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-021-02421-7
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