The stemness of hepatocytes is maintained by high levels of lipopolysaccharide via YAP1 activation

BACKGROUND: The liver possesses a powerful regeneration ability, which is correlated with the stemness of hepatocytes in the portal vein (PV). However, the mechanism underlying the maintenance of hepatocyte stemness has not been elucidated. Here, we hypothesized that high levels of lipopolysaccharid...

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Veröffentlicht in:Stem Cell Res Ther
Hauptverfasser: Shao, Changchun, Yang, Xue, Jing, Yingying, Hou, Xiaojuan, Huang, Yihua, Zong, Chen, Gao, Lu, Liu, Wenting, Jiang, Jinghua, Ye, Fei, Shi, Junxia, Zhao, Qiudong, Li, Rong, Zhang, Xiaoren, Wei, Lixin
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2021
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8193885/
https://ncbi.nlm.nih.gov/pubmed/34112239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-021-02421-7
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