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The stemness of hepatocytes is maintained by high levels of lipopolysaccharide via YAP1 activation

BACKGROUND: The liver possesses a powerful regeneration ability, which is correlated with the stemness of hepatocytes in the portal vein (PV). However, the mechanism underlying the maintenance of hepatocyte stemness has not been elucidated. Here, we hypothesized that high levels of lipopolysaccharid...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Shao, Changchun, Yang, Xue, Jing, Yingying, Hou, Xiaojuan, Huang, Yihua, Zong, Chen, Gao, Lu, Liu, Wenting, Jiang, Jinghua, Ye, Fei, Shi, Junxia, Zhao, Qiudong, Li, Rong, Zhang, Xiaoren, Wei, Lixin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8193885/
https://ncbi.nlm.nih.gov/pubmed/34112239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-021-02421-7
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