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Endothelial cell regulation of systemic haemodynamics and metabolism acts through the HIF transcription factors

BACKGROUND: The vascular endothelium has important endocrine and paracrine roles, particularly in the regulation of vascular tone and immune function, and it has been implicated in the pathophysiology of a range of cardiovascular and inflammatory conditions. This study uses a series of transgenic mu...

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Bibliographic Details
Published in:Intensive Care Med Exp
Main Authors: Lambden, Simon, Cowburn, Andrew S., Macias, David, Garrud, Tessa A. C., Krause, Bernardo J., Giussani, Dino A., Summers, Charlotte, Johnson, Randall S.
Format: Artigo
Language:Inglês
Published: Springer International Publishing 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8192653/
https://ncbi.nlm.nih.gov/pubmed/34114090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40635-021-00390-y
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