Anti-inflammatory Effects of Empagliflozin and Gemigliptin on LPS-Stimulated Macrophage via the IKK/NF-κB, MKK7/JNK, and JAK2/STAT1 Signalling Pathways

BACKGROUND: Sodium-glucose cotransporter 2 (SGLT2) and dipeptidyl peptidase-4 (DPP-4) inhibitors are glucose-lowering drugs whose anti-inflammatory properties have recently become useful in tackling metabolic syndromes in chronic inflammatory diseases, including diabetes and obesity. We investigated...

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Detalhes bibliográficos
Publicado no:J Immunol Res
Main Authors: Lee, Nami, Heo, Yu Jung, Choi, Sung-E, Jeon, Ja Young, Han, Seung Jin, Kim, Dae Jung, Kang, Yup, Lee, Kwan Woo, Kim, Hae Jin
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8192181/
https://ncbi.nlm.nih.gov/pubmed/34124273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/9944880
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