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Identification of 2′-deoxy-2′-fluorocytidine as a potent inhibitor of Crimean-Congo hemorrhagic fever virus replication using a recombinant fluorescent reporter virus

Crimean-Congo hemorrhagic fever virus (CCHFV), a tick-borne orthonairovirus, causes a severe hemorrhagic disease in humans (Crimean-Congo hemorrhagic fever, CCHF). Currently, no vaccines are approved to prevent CCHF; treatment is limited to supportive care and the use of ribavirin, the therapeutic b...

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Detalhes bibliográficos
Publicado no:Antiviral Res
Main Authors: Welch, Stephen R., Scholte, Florine E.M., Flint, Mike, Chatterjee, Payel, Nichol, Stuart T., Bergeron, Éric, Spiropoulou, Christina F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8191813/
https://ncbi.nlm.nih.gov/pubmed/29024765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2017.10.008
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