A single mutation in Crimean-Congo hemorrhagic fever virus discovered in ticks impairs infectivity in human cells

Crimean-Congo hemorrhagic fever (CCHF) is the most widely distributed tick-borne viral infection in the world. Strikingly, reported mortality rates for CCHF are extremely variable, ranging from 5% to 80% (Whitehouse, 2004). CCHF virus (CCHFV, Nairoviridae) exhibits extensive genomic sequence diversi...

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Bibliografiset tiedot
Julkaisussa:eLife
Päätekijät: Hua, Brian L, Scholte, Florine EM, Ohlendorf, Valerie, Kopp, Anne, Marklewitz, Marco, Drosten, Christian, Nichol, Stuart T, Spiropoulou, Christina, Junglen, Sandra, Bergeron, Éric
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: eLife Sciences Publications, Ltd 2020
Aiheet:
Microbiology and Infectious Disease
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7652417/
https://ncbi.nlm.nih.gov/pubmed/33084573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.50999
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