The DNA binding domain of the Vibrio vulnificus SmcR transcription factor is flexible and binds diverse DNA sequences

Quorum sensing gene expression in vibrios is regulated by the LuxR/HapR family of transcriptional factors, which includes Vibrio vulnificus SmcR. The consensus binding site of Vibrio LuxR/HapR/SmcR proteins is palindromic but highly degenerate with sequence variations at each promoter. To examine th...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Newman, Jane D, Russell, Meghan M, Fan, Lixin, Wang, Yun-Xing, Gonzalez-Gutierrez, Giovanni, van Kessel, Julia C
Format: Artigo
Language:Inglês
Published: Oxford University Press 2021
Subjects:
Structural Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8191795/
https://ncbi.nlm.nih.gov/pubmed/34023896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab387
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