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Regulation of Cytotoxicity by Quorum-Sensing Signaling in Vibrio vulnificus Is Mediated by SmcR, a Repressor of hlyU

Cytotoxicity is an important virulence determinant in the pathogenesis of Vibrio vulnificus, and two cytotoxins, RTX (encoded by rtxA1) and cytolysin/hemolysin (encoded by vvhA), have been identified in this organism. We showed that the quorum-sensing regulator LuxO controlled the cytotoxicity of th...

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Autores principales: Shao, Chung-Ping, Lo, Horng-Ren, Lin, Jen-Hsing, Hor, Lien-I
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133160/
https://ncbi.nlm.nih.gov/pubmed/21398530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01259-10
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