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Accurate single-cell genotyping utilizing information from the local genome territory
Single-nucleotide variant (SNV) detection in the genome of single cells is affected by DNA amplification artefacts, including imbalanced alleles and early PCR errors. Existing single-cell genotyper accuracy often depends on the quality and coordination of both the target single-cell and external dat...
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| Veröffentlicht in: | Nucleic Acids Res |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8191788/ https://ncbi.nlm.nih.gov/pubmed/33619552 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab106 |
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