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Accurate human microsatellite genotypes from high-throughput resequencing data using informed error profiles

Repetitive sequences are biologically and clinically important because they can influence traits and disease, but repeats are challenging to analyse using short-read sequencing technology. We present a tool for genotyping microsatellite repeats called RepeatSeq, which uses Bayesian model selection g...

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Detalhes bibliográficos
Main Authors: Highnam, Gareth, Franck, Christopher, Martin, Andy, Stephens, Calvin, Puthige, Ashwin, Mittelman, David
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592458/
https://ncbi.nlm.nih.gov/pubmed/23090981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks981
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