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Post-translational modification of RNA m(6)A demethylase ALKBH5 regulates ROS-induced DNA damage response
Faithful genome integrity maintenance plays an essential role in cell survival. Here, we identify the RNA demethylase ALKBH5 as a key regulator that protects cells from DNA damage and apoptosis during reactive oxygen species (ROS)-induced stress. We find that ROS significantly induces global mRNA N(...
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| Izdano u: | Nucleic Acids Res |
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| Glavni autori: | , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2021
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8191756/ https://ncbi.nlm.nih.gov/pubmed/34048572 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab415 |
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