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Therapeutic Induction of Tertiary Lymphoid Structures in Cancer Through Stromal Remodeling

Improving the effectiveness of anti-cancer immunotherapy remains a major clinical challenge. Cytotoxic T cell infiltration is crucial for immune-mediated tumor rejection, however, the suppressive tumor microenvironment impedes their recruitment, activation, maturation and function. Nevertheless, sol...

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Pubblicato in:Front Immunol
Autori principali: Johansson-Percival, Anna, Ganss, Ruth
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8191417/
https://ncbi.nlm.nih.gov/pubmed/34122434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.674375
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