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The Crohn's-Like Lymphoid Reaction to Colorectal Cancer-Tertiary Lymphoid Structures With Immunologic and Potentially Therapeutic Relevance in Colorectal Cancer

The Crohn's-like lymphoid reaction (CLR) to colorectal cancer (CRC), a CRC-specific ectopic lymphoid reaction, is thought to play an important role in the host response to CRC. CLR is characterized by peritumoral lymphocytic aggregates that are found at the advancing edge of the tumor. Spatial...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Maoz, Asaf, Dennis, Michael, Greenson, Joel K.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6714555/
https://ncbi.nlm.nih.gov/pubmed/31507584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01884
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