Blocking siglec-10(hi) tumor-associated macrophages improves anti-tumor immunity and enhances immunotherapy for hepatocellular carcinoma

BACKGROUND: Tumor-associated macrophages (TAMs) promote key processes in the modulation of tumor microenvironment (TME). However, the clinical significance of heterogeneous subpopulations of TAMs in hepatocellular carcinoma (HCC) remains unknown. METHODS: HCC tissues from Zhongshan Hospital and data...

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Detalhes bibliográficos
Publicado no:Exp Hematol Oncol
Main Authors: Xiao, Nan, Zhu, Xiaodong, Li, Kangshuai, Chen, Yifan, Liu, Xuefeng, Xu, Bin, Lei, Ming, Xu, Jiejie, Sun, Hui-Chuan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8191104/
https://ncbi.nlm.nih.gov/pubmed/34112250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40164-021-00230-5
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