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TBP and SNAP50 transcription factors bind specifically to the Pr77 promoter sequence from trypanosomatid non-LTR retrotransposons

BACKGROUND: Trypanosomatid genomes are colonized by active and inactive mobile DNA elements, such as LINE, SINE-like, SIDER and DIRE retrotransposons. These elements all share a 77-nucleotide-long sequence at their 5′ ends, known as Pr77, which activates transcription, thereby generating abundant un...

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Pubblicato in:Parasit Vectors
Autori principali: Macías, Francisco, Afonso-Lehmann, Raquel, Carreira, Patricia E., Thomas, M. Carmen
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8190864/
https://ncbi.nlm.nih.gov/pubmed/34108018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13071-021-04803-5
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