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The Trypanosomatid Pr77-hallmark contains a downstream core promoter element essential for transcription activity of the Trypanosoma cruzi L1Tc retrotransposon

BACKGROUND: Trypanosomatid genomes are highly colonized by non-LTR retroelements that make up to 5 % of the nuclear genome. These elements are mainly accumulated in the strand switch regions (SSRs) where polycistronic transcription is initiated and have a 77 nt-long sequence - Pr77 - at their 5′ end...

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Publié dans:BMC Genomics
Auteurs principaux: Macías, Francisco, López, Manuel Carlos, Thomas, M. Carmen
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4748587/
https://ncbi.nlm.nih.gov/pubmed/26861854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2427-6
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