Loss of CD96 Expression as a Marker of HIV-Specific CD8(+) T-Cell Differentiation and Dysfunction

Persistent immune activation and inflammation in people living with HIV (PLWH) are associated with immunosenescence, premature aging and increased risk of non-AIDS comorbidities, with the underlying mechanisms not fully understood. In this study, we show that downregulation of the T-cell immunoglobu...

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Vydáno v:Front Immunol
Hlavní autoři: Bunet, Rémi, Nayrac, Manon, Ramani, Hardik, Sylla, Mohamed, Durand, Madeleine, Chartrand-Lefebvre, Carl, Routy, Jean-Pierre, Landay, Alan L., Gauchat, Jean-Francois, Chomont, Nicolas, Ancuta, Petronela, Kaufmann, Daniel E., Bernard, Nicole, Tremblay, Cécile L., El-Far, Mohamed
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8190400/
https://ncbi.nlm.nih.gov/pubmed/34122431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.673061
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