A trispecific killer engager molecule against CLEC12A effectively induces NK cell mediated killing of AML cells

The low five-year survival rate for patients with acute myeloid leukemia (AML), primarily caused due to disease relapse, emphasizes the need for better therapeutic strategies. Disease relapse is facilitated by leukemic stem cells (LSCs) that are resistant to standard chemotherapy and promote tumor g...

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Udgivet i:Leukemia
Main Authors: Arvindam, Upasana Sunil, van Hauten, Paulien M.M., Schirm, Dawn, Schaap, Nicolaas, Hobo, Willemijn, Blazar, Bruce R., Vallera, Daniel A., Dolstra, Harry, Felices, Martin, Miller, Jeffrey S.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8189652/
https://ncbi.nlm.nih.gov/pubmed/33097838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-020-01065-5
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