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A method for systematically ranking therapeutic drug candidates using multiple uncertain screening criteria

Multiple different screening tests for candidate leads in drug development may often yield conflicting or ambiguous results, sometimes making the selection of leads a nontrivial maximum-likelihood ranking problem. Here, we employ methods from the field of multiple criteria decision making (MCDM) to...

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Bibliografiska uppgifter
I publikationen:Stat Methods Med Res
Huvudupphovsmän: Peng, Xubiao, Gibbs, Ebrima, Silverman, Judith M, Cashman, Neil R, Plotkin, Steven S
Materialtyp: Artigo
Språk:Inglês
Publicerad: SAGE Publications 2021
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8189013/
https://ncbi.nlm.nih.gov/pubmed/33847541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/09622802211002861
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