Raloxifene retards the progression of adjacent segmental intervertebral disc degeneration by inhibiting apoptosis of nucleus pulposus in ovariectomized rats

BACKGROUND: Adjacent segmental intervertebral disk degeneration (ASDD) is a major complication secondary to lumbar fusion. Although ASSD pathogenesis remains unclear, the primary cause of intervertebral disk degeneration (IVDD) development is apoptosis of nucleus pulposus (NP). Raloxifene (RAL) coul...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Orthop Surg Res
Prif Awduron: Sun, Qi, Nan, Xin-Yu, Tian, Fa-Ming, Liu, Fang, Ping, Shao-Hua, Zhou, Zhuang, Zhang, Liu
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2021
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8188785/
https://ncbi.nlm.nih.gov/pubmed/34107971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13018-021-02504-4
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