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A review of the biological and clinical implications of RAS-MAPK pathway alterations in neuroblastoma

Neuroblastoma is the most common extra-cranial solid tumor in children, representing approximately 8% of all malignant childhood tumors and 15% of pediatric cancer-related deaths. Recent sequencing and transcriptomics studies have demonstrated the RAS-MAPK pathway’s contribution to the development a...

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Detalles Bibliográficos
Publicado en:J Exp Clin Cancer Res
Main Authors: Mlakar, Vid, Morel, Edouard, Mlakar, Simona Jurkovic, Ansari, Marc, Gumy-Pause, Fabienne
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8188681/
https://ncbi.nlm.nih.gov/pubmed/34103089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-021-01967-x
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