Glycoproteomics identifies HOMER3 as a potentially targetable biomarker triggered by hypoxia and glucose deprivation in bladder cancer

BACKGROUND: Muscle invasive bladder cancer (MIBC) remains amongst the deadliest genitourinary malignancies due to treatment failure and extensive molecular heterogeneity, delaying effective targeted therapeutics. Hypoxia and nutrient deprivation, oversialylation and O-glycans shortening are salient...

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Dettagli Bibliografici
Pubblicato in:J Exp Clin Cancer Res
Autori principali: Peixoto, Andreia, Ferreira, Dylan, Azevedo, Rita, Freitas, Rui, Fernandes, Elisabete, Relvas-Santos, Marta, Gaiteiro, Cristiana, Soares, Janine, Cotton, Sofia, Teixeira, Beatriz, Paulo, Paula, Lima, Luís, Palmeira, Carlos, Martins, Gabriela, Oliveira, Maria José, Silva, André M. N., Santos, Lúcio Lara, Ferreira, José Alexandre
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2021
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8188679/
https://ncbi.nlm.nih.gov/pubmed/34108014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-021-01988-6
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