Nucleolin-Sle A Glycoforms as E-Selectin Ligands and Potentially Targetable Biomarkers at the Cell Surface of Gastric Cancer Cells

Background: Gastric cancer (GC) is a major health burden worldwide, with half of patients developing metastases within 5 years after treatment, urging novel biomarkers for diagnosis and efficient therapeutic targeting. Sialyl-Lewis A (SLeA), a terminal glycoepitope of glycoproteins and glycolipids,...

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Udgivet i:Cancers (Basel)
Main Authors: Fernandes, Elisabete, Freitas, Rui, Ferreira, Dylan, Soares, Janine, Azevedo, Rita, Gaiteiro, Cristiana, Peixoto, Andreia, Oliveira, Sara, Cotton, Sofia, Relvas-Santos, Marta, Afonso, Luis Pedro, Palmeira, Carlos, Oliveira, Maria José, Ferreira, Rita, Silva, André M. N., Lara Santos, Lúcio, Ferreira, José Alexandre
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226152/
https://ncbi.nlm.nih.gov/pubmed/32252346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12040861
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