Dimethyl fumarate reduces hepatocyte senescence following paracetamol exposure

Liver disease is a major cause of premature death. Oxidative stress in the liver represents a key disease driver. Compounds, such as dimethyl fumarate (DMF), can activate the antioxidant response and are used clinically to treat disease. In this study, we tested the protective properties of DMF befo...

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Publicat a:iScience
Autors principals: Meseguer-Ripolles, Jose, Lucendo-Villarin, Baltasar, Tucker, Carl, Ferreira-Gonzalez, Sofia, Homer, Natalie, Wang, Yu, Starkey Lewis, Philip J., M Toledo, Enrique, Mellado-Gomez, Esther, Simpson, Joanna, Flint, Oliver, Jaiswal, Himjyot, Beer, Nicola L., Karlsen, Allan E., Forbes, Stuart J., Dear, James W., Hughes, Jeremy, Hay, David C.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8188562/
https://ncbi.nlm.nih.gov/pubmed/34151225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102552
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