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SPARC regulation of PMN clearance protects from pristane-induced lupus and rheumatoid arthritis
The secreted protein acidic and rich in cysteine (SPARC) is a matricellular protein with unexpected immunosuppressive function in myeloid cells. We investigated the role of SPARC in autoimmunity using the pristane-induced model of lupus that, in mice, mimics human systemic lupus erythematosus (SLE)....
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| Опубликовано в: : | iScience |
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| Главные авторы: | , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Elsevier
2021
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8188360/ https://ncbi.nlm.nih.gov/pubmed/34142027 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102510 |
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