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Targeted RNA N (6)‐Methyladenosine Demethylation Controls Cell Fate Transition in Human Pluripotent Stem Cells

Deficiency of the N (6)‐methyladenosine (m(6)A) methyltransferase complex results in global reduction of m(6)A abundance and defective cell development in embryonic stem cells (ESCs). However, it's unclear whether regional m(6)A methylation affects cell fate decisions due to the inability to mo...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Adv Sci (Weinh)
Hauptverfasser: Chen, Xuena, Zhao, Qingquan, Zhao, Yu‐Li, Chai, Guo‐Shi, Cheng, Weisheng, Zhao, Zhiju, Wang, Jia, Luo, Guan‐Zheng, Cao, Nan
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8188216/
https://ncbi.nlm.nih.gov/pubmed/34105279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.202003902
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