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Targeted RNA N (6)‐Methyladenosine Demethylation Controls Cell Fate Transition in Human Pluripotent Stem Cells

Deficiency of the N (6)‐methyladenosine (m(6)A) methyltransferase complex results in global reduction of m(6)A abundance and defective cell development in embryonic stem cells (ESCs). However, it's unclear whether regional m(6)A methylation affects cell fate decisions due to the inability to mo...

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Podrobná bibliografie
Vydáno v:Adv Sci (Weinh)
Hlavní autoři: Chen, Xuena, Zhao, Qingquan, Zhao, Yu‐Li, Chai, Guo‐Shi, Cheng, Weisheng, Zhao, Zhiju, Wang, Jia, Luo, Guan‐Zheng, Cao, Nan
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8188216/
https://ncbi.nlm.nih.gov/pubmed/34105279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.202003902
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