NaHS or Lovastatin Attenuates Cyclosporine A–Induced Hypertension in Rats by Inhibiting Epithelial Sodium Channels

The use of cyclosporine A (CsA) in transplant recipients is limited due to its side effects of causing severe hypertension. We have previously shown that CsA increases the activity of the epithelial sodium channel (ENaC) in cultured distal nephron cells. However, it remains unknown whether ENaC medi...

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Dades bibliogràfiques
Publicat a:Front Pharmacol
Autors principals: Wang, Qiu-Shi, Liang, Chen, Jiang, Shuai, Zhu, Di, Sun, Yu, Niu, Na, Yang, Xu, Yang, Yan-Chao, Dong, Bi-Han, Yao, Jie, Yu, Chang-Jiang, Lou, Jie, Tang, Liang-Liang, Wu, Ming-Ming, Zhang, Zhi-Ren, Ma, He-Ping
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8187945/
https://ncbi.nlm.nih.gov/pubmed/34122084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.665111
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