NaHS or Lovastatin Attenuates Cyclosporine A–Induced Hypertension in Rats by Inhibiting Epithelial Sodium Channels

The use of cyclosporine A (CsA) in transplant recipients is limited due to its side effects of causing severe hypertension. We have previously shown that CsA increases the activity of the epithelial sodium channel (ENaC) in cultured distal nephron cells. However, it remains unknown whether ENaC medi...

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Bibliografski detalji
Izdano u:Front Pharmacol
Glavni autori: Wang, Qiu-Shi, Liang, Chen, Jiang, Shuai, Zhu, Di, Sun, Yu, Niu, Na, Yang, Xu, Yang, Yan-Chao, Dong, Bi-Han, Yao, Jie, Yu, Chang-Jiang, Lou, Jie, Tang, Liang-Liang, Wu, Ming-Ming, Zhang, Zhi-Ren, Ma, He-Ping
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2021
Teme:
Pharmacology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8187945/
https://ncbi.nlm.nih.gov/pubmed/34122084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.665111
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