A novel mouse AAV6 hACE2 transduction model of wild-type SARS-CoV-2 infection studied using synDNA immunogens

More than 100 million people have been infected with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Common laboratory mice are not susceptible to wild-type SARS-CoV-2 infection, challenging the development and testing of effective interventions. Here, we describe the development and t...

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Publicat a:iScience
Autors principals: Gary, Ebony N., Warner, Bryce M., Parzych, Elizabeth M., Griffin, Bryan D., Zhu, Xizhou, Tailor, Nikesh, Tursi, Nicholas J., Chan, Mable, Purwar, Mansi, Vendramelli, Robert, Choi, Jihae, Frost, Kathy L., Reeder, Sophia, Liaw, Kevin, Tello, Edgar, Ali, Ali R., Yun, Kun, Pei, Yanlong, Thomas, Sylvia P., Rghei, Amira D., Guilleman, Matthew M., Muthumani, Kar, Smith, Trevor, Wootton, Sarah K., Patel, Ami, Weiner, David B., Kobasa, Darwyn
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8186956/
https://ncbi.nlm.nih.gov/pubmed/34124612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102699
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