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RSC primes the quiescent genome for hypertranscription upon cell-cycle re-entry

Quiescence is a reversible G(0) state essential for differentiation, regeneration, stem-cell renewal, and immune cell activation. Necessary for long-term survival, quiescent chromatin is compact, hypoacetylated, and transcriptionally inactive. How transcription activates upon cell-cycle re-entry is...

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發表在:eLife
Main Authors: Cucinotta, Christine E, Dell, Rachel H, Braceros, Keean CA, Tsukiyama, Toshio
格式: Artigo
語言:Inglês
出版: eLife Sciences Publications, Ltd 2021
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8186906/
https://ncbi.nlm.nih.gov/pubmed/34042048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.67033
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