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Nicotine promotes the development of oral leukoplakia via regulating peroxiredoxin 1 and its binding proteins
Tobacco can induce reactive oxygen species (ROS) production extensively in cells, which is a major risk factor for oral leukoplakia (OLK) development. Peroxiredoxin 1 (Prx1) is a key antioxidant protein, upregulated in a variety of malignant tumors. We previously found that nicotine, the main ingred...
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| Publicado en: | Braz J Med Biol Res |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Associação Brasileira de Divulgação Científica
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8186375/ https://ncbi.nlm.nih.gov/pubmed/34076143 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/1414-431X2020e10931 |
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