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Nicotine promotes the development of oral leukoplakia via regulating peroxiredoxin 1 and its binding proteins

Tobacco can induce reactive oxygen species (ROS) production extensively in cells, which is a major risk factor for oral leukoplakia (OLK) development. Peroxiredoxin 1 (Prx1) is a key antioxidant protein, upregulated in a variety of malignant tumors. We previously found that nicotine, the main ingred...

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Bibliografische gegevens
Gepubliceerd in:Braz J Med Biol Res
Hoofdauteurs: Qi, Moci, Li, Lingyu, Tang, Xiaofei, Lu, Yunping, Wang, Min, Yang, Jing, Zhang, Min
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Associação Brasileira de Divulgação Científica 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8186375/
https://ncbi.nlm.nih.gov/pubmed/34076143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/1414-431X2020e10931
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