Peroxiredoxin1 Knockdown Inhibits Oral Carcinogenesis via Inducing Cell Senescence Dependent on Mitophagy

PURPOSE: Cellular senescence is a physiological phenomenon by which cells irreversibly lose their proliferative potential. It is not clear whether senescent cells are related to malignant transformation in oral precancerous lesions. The role of peroxiredoxin1 (Prx1)-induced cell senescence in OLK ma...

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Bibliographic Details
Published in:Onco Targets Ther
Main Authors: Lu, Yunping, Li, Lingyu, Chen, Hui, Jing, Xinying, Wang, Min, Ge, Lihua, Yang, Jing, Zhang, Min, Tang, Xiaofei
Format: Artigo
Language:Inglês
Published: Dove 2021
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7812030/
https://ncbi.nlm.nih.gov/pubmed/33469304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S284182
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