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Peroxiredoxin1 Knockdown Inhibits Oral Carcinogenesis via Inducing Cell Senescence Dependent on Mitophagy

PURPOSE: Cellular senescence is a physiological phenomenon by which cells irreversibly lose their proliferative potential. It is not clear whether senescent cells are related to malignant transformation in oral precancerous lesions. The role of peroxiredoxin1 (Prx1)-induced cell senescence in OLK ma...

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Bibliografische gegevens
Gepubliceerd in:Onco Targets Ther
Hoofdauteurs: Lu, Yunping, Li, Lingyu, Chen, Hui, Jing, Xinying, Wang, Min, Ge, Lihua, Yang, Jing, Zhang, Min, Tang, Xiaofei
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Dove 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7812030/
https://ncbi.nlm.nih.gov/pubmed/33469304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S284182
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