Agarose microgel culture delineates lumenogenesis in naive and primed human pluripotent stem cells

Human periimplantation development requires the transformation of the naive pluripotent epiblast into a polarized epithelium. Lumenogenesis plays a critical role in this process, as the epiblast undergoes rosette formation and lumen expansion to form the amniotic cavity. Here, we present a high-thro...

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Publicado en:Stem Cell Reports
Main Authors: Schindler, Magdalena, Siriwardena, Dylan, Kohler, Timo N., Ellermann, Anna L., Slatery, Erin, Munger, Clara, Hollfelder, Florian, Boroviak, Thorsten E.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8185981/
https://ncbi.nlm.nih.gov/pubmed/33979603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2021.04.009
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