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Single-Shot, Multicycle Suicide Gene Therapy by Replication-Competent Retrovirus Vectors Achieves Long-Term Survival Benefit in Experimental Glioma

Achieving therapeutically efficacious levels of gene transfer in tumors has been a major obstacle for cancer gene therapy using replication-defective virus vectors. Recently, replicating viruses have emerged as attractive tools for cancer therapy, but generally achieve only transitory tumor regressi...

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Publicat a:Mol Ther
Autors principals: Tai, Chien-Kuo, Wang, Wei Jun, Chen, Thomas C., Kasahara, Noriyuki
Format: Artigo
Idioma:Inglês
Publicat: 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8185609/
https://ncbi.nlm.nih.gov/pubmed/16257382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2005.03.017
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