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Perampanel, an AMPAR antagonist, alleviates experimental intracerebral hemorrhage-induced brain injury via necroptosis and neuroinflammation

Spontaneous intracerebral hemorrhage (ICH) is a subtype of stroke with high mortality and morbidity due to the lack of effective therapies. The alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antagonist perampanel has been reported to alleviate early brain injury following subarach...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Yang, Lixiang, Wang, Yue, Zhang, Can, Cheng, Huilin
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8185517/
https://ncbi.nlm.nih.gov/pubmed/34080030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2021.12183
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