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The AMPAR antagonist perampanel protects the neurovascular unit against traumatic injury via regulating Sirt3

INTRODUCTION: Perampanel is a highly selective and noncompetitive α‐amino‐3 ‐hydroxy‐5‐methyl‐4‐isoxazole propionate receptor (AMPAR) antagonist, which has been used as an orally administered antiepileptic drug in more than 55 countries. Recently, perampanel was shown to exert neuroprotective effect...

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Detalhes bibliográficos
Publicado no:CNS Neurosci Ther
Main Authors: Chen, Tao, Liu, Wen‐Bo, Qian, Xiao, Xie, Ke‐Liang, Wang, Yu‐Hai
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7804923/
https://ncbi.nlm.nih.gov/pubmed/33421349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.13580
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