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Gene expression dynamics underlying cell fate emergence in 2D micropatterned human embryonic stem cell gastruloids

Human embryonic stem cells cultured in 2D micropatterns with BMP4 differentiate into a radial arrangement of germ layers and extraembryonic cells. Single-cell transcriptomes demonstrate generation of cell types transcriptionally similar to their in vivo counterparts in Carnegie stage 7 human gastrul...

詳細記述

保存先:
書誌詳細
出版年:Stem Cell Reports
主要な著者: Minn, Kyaw Thu, Dietmann, Sabine, Waye, Sarah E., Morris, Samantha A., Solnica-Krezel, Lilianna
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8185470/
https://ncbi.nlm.nih.gov/pubmed/33891870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2021.03.031
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