Ex Vivo–Induced Bone Marrow-Derived Myeloid Suppressor Cells Prevent Corneal Allograft Rejection in Mice

PURPOSE: To investigate the effects of ex vivo–induced bone marrow myeloid-derived suppressor cells (BM-MDSCs) on allogeneic immune responses in corneal transplantation. METHODS: Bone marrow cells from C57BL/6J (B6) mice were cultured with IL-6 and GM-CSF for four days. The ex vivo induction of the...

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Dettagli Bibliografici
Pubblicato in:Invest Ophthalmol Vis Sci
Autori principali: Zhu, Jun, Inomata, Takenori, Fujimoto, Keiichi, Uchida, Koichiro, Fujio, Kenta, Nagino, Ken, Miura, Maria, Negishi, Naoko, Okumura, Yuichi, Akasaki, Yasutsugu, Hirosawa, Kunihiko, Kuwahara, Mizu, Eguchi, Atsuko, Shokirova, Hurramhon, Yanagawa, Ai, Midorikawa-Inomata, Akie, Murakami, Akira
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Association for Research in Vision and Ophthalmology 2021
Soggetti:
Cornea
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8185403/
https://ncbi.nlm.nih.gov/pubmed/34061951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.62.7.3
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