Efficient conversion of human induced pluripotent stem cells into microglia by defined transcription factors

Microglia, the immune cells of the central nervous system, play critical roles in brain physiology and pathology. We report a novel approach that produces, within 10 days, the differentiation of human induced pluripotent stem cells (hiPSCs) into microglia (iMG) by forced expression of both SPI1 and...

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Bibliografske podrobnosti
izdano v:Stem Cell Reports
Main Authors: Chen, Shih-Wei, Hung, Yu-Sheng, Fuh, Jong-Ling, Chen, Nien-Jung, Chu, Yeh-Shiu, Chen, Shu-Cian, Fann, Ming-Ji, Wong, Yu-Hui
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2021
Teme:
Resource
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8185376/
https://ncbi.nlm.nih.gov/pubmed/33836143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2021.03.010
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