Efficient conversion of human induced pluripotent stem cells into microglia by defined transcription factors

Microglia, the immune cells of the central nervous system, play critical roles in brain physiology and pathology. We report a novel approach that produces, within 10 days, the differentiation of human induced pluripotent stem cells (hiPSCs) into microglia (iMG) by forced expression of both SPI1 and...

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Publicado no:Stem Cell Reports
Main Authors: Chen, Shih-Wei, Hung, Yu-Sheng, Fuh, Jong-Ling, Chen, Nien-Jung, Chu, Yeh-Shiu, Chen, Shu-Cian, Fann, Ming-Ji, Wong, Yu-Hui
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8185376/
https://ncbi.nlm.nih.gov/pubmed/33836143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2021.03.010
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