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D-dopachrome tautomerase contributes to lung epithelial repair via atypical chemokine receptor 3-dependent Akt signaling

BACKGROUND: Emphysematous COPD is characterized by aberrant alveolar repair. Macrophage migration inhibitory factor (MIF) contributes to alveolar repair, but for its structural and functional homolog D-dopachrome tautomerase (DDT) this is unknown. MIF mediates its effects through CD74 and/or C-X-C c...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Song, Shanshan, Liu, Bin, Habibie, Habibie, van den Bor, Jelle, Smit, Martine J., Gosens, Reinoud, Wu, Xinhui, Brandsma, Corry-Anke, Cool, Robbert H., Haisma, Hidde J., Poelarends, Gerrit J., Melgert, Barbro N.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8185224/
https://ncbi.nlm.nih.gov/pubmed/34098338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2021.103412
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